Wednesday, 18 April 2018

ECG of the Week - 16th April 2018 - Interpretation

The following ECG is from a 19 yr old referred by their GP for investigation of palpitations found at a routine medical review. The patient is asymptomatic with no past medical history or regular medications.


  
Click to enlarge
Rate:
  • Mean ventricular rate 60 bpm
Rhythm:
  • Complicated and difficult to fully ascertain on a single ECG
  • Atrial activity seen
    • P waves clearly visible
    • Variable P-P interval 
    • Apparent drop of P waves before 2nd, 3rd, and 4th ventricular ectopics
    • I think the P waves are actually buried in the initial portion of the wide QRS best appreciated in the 4th ventricular ectopic (green circle) rather than representing SA exit block.
Lead II
P waves labelled Red line
P wave buried in PVC Green circle
  • Evidence of AV block
    • Multiple non-conducted P waves
    • No progressive PR prolongation evident - longer rhythm strip would be helpful
    • 2nd Degree AV Block Mobitz II
  • Frequent PVC's
    • 4 During 10 second recording
    • Likely unifocal
    • 1st PVC likely has some fusion due to proximity to preceeding P wave
Axis (Conducted QRS):
  • Normal
Intervals (Conducted QRS):
  • PR - Prolonged (220ms)
  • QRS - Normal
  • QT - 340ms
The ECG in Athlete's

There are a number of adaptive physiological changes seen in athlete's as a response to regular exercise including cardiac changes such as change in LV wall thickness or end-diastolic LV volume (Lisman KA). These physiological adaptations can also be manifest as changes on the 12-lead ECG.
The challenge for clinicians is picking those changes that require further investigation for potential causes of sudden cardiac death versus those that represent normal adaptation.
Thankfully there is an Consensus International Criteria for ECG Interpretation in Athletes, aka 'Seattle criteria', developed in 2015 with the latest version published in BJSM in 2017.
It provides guidance on those ECG features that can be considered a normal response to exercise, those that are 'borderline' and those that require further investigation. The updated version also provided guidance on differentials associated with each ECG abnormality and appropriate investigation modalities. The following flow chart summaries these groups of ECG findings:
 
Taken from Drezner JA, Sharma S, Baggish A, et al. International criteria for electrocardiographic interpretation in athletes: Consensus statement. Br J Sports Med 2017;51:704-731
In Our Case

The abnormal findings seen on this ECG:

  • Frequent PVC's - 4 seen in 10 second window equating to up to ~35000/day 
  • Mobitz II AV Block


Differential causes for these features include:
  • Arrhythmogenic Right Ventricular Cardiomyopathy - can genetic or induced
  • Left Ventricular Non-Compaction
  • Dilated Cardiomyopathy
  • Hypertrophic Cardiomyopathy
  • Sarcoidosis
  • Myocarditis
This patient was referred for further cardiac investigation which may include echo, 24-holter, ILR, EP study and cardiac MRI

References / Further Reading
References

Textbook
  • Chan TC, Brady WJ, Harrigan RA, Ornato JP, Rosen P. ECG in Emergency Medicine and Acute Care. Elsevier Mosby 2005.